Frankfort, KY – Multi-Vehicle Crash on I-64 Leaves 3 Dead, Several Hurt

Frankfort, KY (September 15, 2025) – A tragic multi-vehicle crash on Interstate 64 in Woodford County claimed three lives and left several others injured on Saturday night, September 13. The Kentucky State Police reported that the collision happened around 7:30 p.m. near the 61-mile marker in the westbound lanes.

According to investigators, the crash involved four tractor-trailers and two passenger cars. The impact caused severe damage and sparked a fire at the scene, complicating emergency response efforts. Two of the tractor-trailer drivers and one passenger vehicle occupant were pronounced dead at the scene.

Paramedics transported two other passenger vehicle occupants and one commercial driver to local hospitals with injuries. Officials have not released the identities of the victims as the investigation continues. Due to the complexity of the crash and the number of vehicles involved, police expect the investigation to take time before all details are made public.

The investigation into this fatal crash remains ongoing.

Our deepest condolences go out to the families of those who lost their lives in this crash, and we also hope for a full recovery for those who were injured. 

Truck Accidents in Kentucky

Collisions involving tractor-trailers are among the most devastating accidents on Kentucky highways. Large trucks outweigh passenger cars by tens of thousands of pounds, and when multiple commercial vehicles are involved, the results can be catastrophic. Victims often face severe injuries, loss of loved ones, and long-term hardships.

Common causes of multi-vehicle truck accidents include:

• Driver fatigue from long hours behind the wheel
• Distracted driving or inattention on busy interstates
• Speeding or unsafe lane changes
• Improperly loaded cargo that shifts during travel
• Mechanical failures or poor vehicle maintenance

Victims of these crashes and their families may pursue compensation for their losses through a wrongful death claim. A brave and compassionate wrongful death attorney can help by investigating the collision, reviewing driver logs and trucking company records, and building a strong case against negligent parties. Compensation may cover medical expenses, funeral costs, lost income, and damages for pain and suffering.

Because of the involvement of multiple vehicles and trucking companies, these cases can become extremely complex. Having a knowledgeable lawyer ensures victims and families understand their rights and have an advocate protecting their interests.

At Byrnes Law Office, we know how devastating truck accidents can be for Kentucky families. Our team works tirelessly to hold negligent drivers and companies accountable for the harm they cause. At Byrnes Law Office, we fight to secure justice and the maximum compensation for our clients.

If you have been injured or a loved one has unexpectedly passed away due to a serious crash, do not wait to get legal guidance. Call Byrnes Law Office today at (502) 364-2500 for a free consultation. We are here to stand with you and fight for your rights.

Note: Our writers use external sources such as news briefs, police scanners, and eyewitness reports when creating this post. While we aim for accuracy, the information hasn't been independently verified by our team. If you spot any errors, please inform us promptly for correction. If you'd like the post removed, please contact us, and we'll act swiftly. Your feedback helps us uphold our standards.

Disclaimer: Byrnes Law Office is dedicated to improving safety for Kentucky drivers. Our goal is to raise awareness about the dangers of driving and the need to use caution. This is not a solicitation for business, and none of the information constitutes legal or medical advice. Photos in this post are not of the actual accident scene.